대한흉부영상의학회 Weekly Chest Cases

Courtesy of Hye Soo Cho, Ji Young Lee, Woo Hyeon Lim / Seoul National University Hospital
Age/Sex 59 / M
Chief ComplaintFever / Brief history: Myelodysplastic syndrome, Acute myeloid leukemia, s/p Haplo-PBSCT

Diagnosis: Posttransplant lymphoproliferative disorder
Radiologic Findings: Fig 1. Chest PA shows multifocal ill defined opacities in both lung fields.
Fig 2. Chest CT scan shows ill-defined GGOs in both lung.
Fig 3-5. In chest CT, multifocal GGO and consolidation have been gradually aggravated during follow-ups despite the empirical treatment.
Brief Review: Post-transplantation lymphoproliferative disorders (PTLDs) are defined as lymphomas that occur after transplantation. PTLD is the second most common tumor in adult transplant recipients. Recipients of solid-organ or allogeneic hematopoietic stem-cell transplants have an increased risk of cancers related to immunosuppression and the Epstein
References: 1. Dierickx D, Habermann TM. Post-Transplantation Lymphoproliferative Disorders in Adults. N Engl J Med. 2018 Feb 8;378(6):549-562.
2. Borhani AA, Hosseinzadeh K, Almusa O, Furlan A, Nalesnik M. Imaging of posttransplantation lymphoproliferative disorder after solid organ transplantation. Radiographics. 2009 Jul-Aug;29(4):981-1000.
3. Camacho JC, Moreno CC, Harri PA, Aguirre DA, Torres WE, Mittal PK. Posttransplantation lymphoproliferative disease: proposed imaging classification. Radiographics. 2014 Nov-Dec;34(7):2025-38.
Keywords

- The University of Tokyo Hospital , Japan JUN KANZAWA
- Vita Hospital , Brazil DIOGO LAGO PINHEIRO
- university of montreal , Canada Andrei Bogdan Gorgos I
- Ajou University Hospital , Korea (South) HAEIN LEE
- The Catholic University of Korea Yoeuido St. Mary , Korea (South) CHAWOONG JEON

대한흉부영상의학회 Korean Society of Thoracic Radiology